Featured Publications
Get to know some of the latest publications by our faculties.
Impact of Antibiotics on the Lung Microbiome and Lung Function in Children With Cystic Fibrosis 1 Year After Hospitalization for an Initial Pulmonary Exacerbation
October 4, 2023
The purpose of this study was to evaluate changes in the microbiome and lung function in people with CF over 1 year after an initial pulmonary exacerbation.
Integrated Fertilization with Bagasse Vermicompost Changes the Microbiome of Mencía Must and Wine
October 4, 2023
Grape marc, or bagasse, is a byproduct of wine production that can be vermicomposted and used as organic fertilizer, which improve grape yields and wine quality
Nasopharyngeal metatranscriptome profiles of infants with bronchiolitis and risk of childhood asthma: a multicentre prospective study
October 4, 2023
Our objectives were to identify metatranscriptome profiles of infant bronchiolitis, and to examine relationship with host transcriptome and asthma development.
Orienting Ordered Scaffolds: Complexity and Algorithms
October 4, 2023
We address the problem of orientating ordered scaffolds as an optimization problem based on given weighted orientations of scaffolds and their pairs.
Integrated relationship of nasopharyngeal airway host response and microbiome associates with bronchiolitis severity
October 4, 2023
Bronchiolitis is a leading cause of infant hospitalizations but its immunopathology remains poorly understood.
Metabolite, protein, and tissue dysfunction associated with COVID‑19 disease severity
October 4, 2023
Proteins are direct products of the genome and metabolites are functional products of interactions between the host and other factors.
High-sensitivity pattern discovery in large, paired multiomic datasets
October 4, 2023
We present a novel framework which integrates hierarchical hypothesis testing with FDR correction to reveal linear and non-linear relationships among data.
Association of Early Aspirin Use With In-Hospital Mortality in Patients With Moderate COVID-19
October 4, 2023
Prior studies suggest aspirin may be associated with reduced mortality in high-risk patients with COVID-19, but patients with moderate COVID-19 are not studied.
546 Therapeutic beta-lactam dosages and broad-spectrum antibiotics are associated with short-term reductions in microbial richness and beta-diversity
October 4, 2023
People with cystic fibrosis have morbid pulmonary exacerbations. Antibiotics are common, yet the beta-lactam doses administered are less than half the time.
Host taxonomy determines the composition, structure, and diversity of the earthworm cast microbiome under homogenous feeding conditions
October 4, 2023
Host evolutionary history is a key factor shaping the earthworm cast microbiome, although its effect can be shadowed by the earthworm’s diet.
Induction of mastitis by cow-to-mouse fecal and milk microbiota transplantation causes microbiome dysbiosis and genomic functional perturbation in mice
October 4, 2023
To understand the host-tropism phenomena of bovine-tropic mastitis microbiomes, we developed a cow-to-mouse mastitis model.
Differential expression of single-cell RNA-seq data using Tweedie models
October 4, 2023
To model the technological variability in cross-platform scRNA-seq data, here we propose to use Tweedie generalized linear models.