Featured Publications

Get to know some of the latest publications by our faculties.

 

Estimating rare disease prevalence and costs in the USA: a cohort study approach using the Healthcare Cost Institute claims data

May 30, 2024

Estimating rare disease prevalence and costs in the USA: a cohort study approach using the Healthcare Cost Institute claims data

Integrated relationship of nasopharyngeal airway host response and microbiome associates with bronchiolitis severity

May 30, 2024

Bronchiolitis is a leading cause of infant hospitalizations but its immunopathology remains poorly understood.

Metabolite, protein, and tissue dysfunction associated with COVID‑19 disease severity

May 30, 2024

Proteins are direct products of the genome and metabolites are functional products of interactions between the host and other factors.

High-sensitivity pattern discovery in large, paired multiomic datasets

May 30, 2024

We present a novel framework which integrates hierarchical hypothesis testing with FDR correction to reveal linear and non-linear relationships among data.

Association of Early Aspirin Use With In-Hospital Mortality in Patients With Moderate COVID-19

May 30, 2024

Prior studies suggest aspirin may be associated with reduced mortality in high-risk patients with COVID-19, but patients with moderate COVID-19 are not studied.

546 Therapeutic beta-lactam dosages and broad-spectrum antibiotics are associated with short-term reductions in microbial richness and beta-diversity

May 30, 2024

People with cystic fibrosis have morbid pulmonary exacerbations. Antibiotics are common, yet the beta-lactam doses administered are less than half the time.

Host taxonomy determines the composition, structure, and diversity of the earthworm cast microbiome under homogenous feeding conditions

May 30, 2024

Host evolutionary history is a key factor shaping the earthworm cast microbiome, although its effect can be shadowed by the earthworm’s diet.

Induction of mastitis by cow-to-mouse fecal and milk microbiota transplantation causes microbiome dysbiosis and genomic functional perturbation in mice

May 30, 2024

To understand the host-tropism phenomena of bovine-tropic mastitis microbiomes, we developed a cow-to-mouse mastitis model.

Differential expression of single-cell RNA-seq data using Tweedie models

May 30, 2024

To model the technological variability in cross-platform scRNA-seq data, here we propose to use Tweedie generalized linear models.

Chromosome-level genome assemblies of the malaria vectors Anopheles coluzzii and Anopheles arabiensis

May 30, 2024

We produced chromosome-level genome assemblies for A. coluzzii and A. arabiensis using Oxford Nanopore sequencing technology and Hi-C scaffolding approach.

Impact of Antibiotics on the Lung Microbiome and Lung Function in Children With Cystic Fibrosis 1 Year After Hospitalization for an Initial Pulmonary Exacerbation

May 30, 2024

The purpose of this study was to evaluate changes in the microbiome and lung function in people with CF over 1 year after an initial pulmonary exacerbation.

Integrated Fertilization with Bagasse Vermicompost Changes the Microbiome of Mencía Must and Wine

May 30, 2024

Grape marc, or bagasse, is a byproduct of wine production that can be vermicomposted and used as organic fertilizer, which improve grape yields and wine quality