Computational Biology Institute

Induction of mastitis by cow-to-mouse fecal and milk microbiota transplantation causes microbiome dysbiosis and genomic functional perturbation in mice

July 6, 2022

Taxonomic composition of bacteriomes. Venn diagrams representing the core unique and shared microbiomes in cows faecal material and milk samples, and mouse faecal material and mammary tissues. Bacterial species detected in A cows faecal material, B cows milk, C mouse faecal material and D mouse mammary tissues. E Unique and shared bacterial species in CM, and F unique and shared bacterial species in H metagenomes of both cows and mice. Bacterial species shared in cow and mouse mastitis

To understand the host-tropism phenomena of bovine-tropic mastitis microbiomes, we developed a cow-to-mouse mastitis model.