Register now for the 2017 BioHealth
Capital Region Forum! Click on the
image above for more information!
The Capital Area Advanced Research
and Education Network is an initiative
designed to build a high-performance
research and education infrastructure
serving the Washington, DC, and
Northern Virginia areas. CAAREN
will facilitate world-class research,
education and knowledge sharing in
the nation’s capital. Click the image
above to learn more!
CBI Transitions to the Milken Institute School of Public Health
The Computational Biology Institute is highlighted in the Milken Institute School of Public Health's "2016 Progress Report" as we make the exciting transition into the organization. Check us out on page 17!
About the CBI
The Department of Mathematical Sciences of George Mason University will host a 4-day Mason Modeling Days workshop June 28-July 1, 2017, in Arlington, VA. To learn more, click on the link above.
The CBW has developed a three-day workshop, taking place July 10-12, providing an introduction to RNA-seq data analysis followed by integrated tutorials demonstrating the use of popular RNA-seq analysis packages. For more information, click on the link above.
Join researchers and leaders from academia, hospitals, government and industry for two days at Stanford Medicine to spark collaborations, address challenges, and identify actionable steps for using large-scale data analysis and technology to improve human health. See the event webpage above!
Reconstruction of Ancestral Genomes in Presence of Gene Gain and Loss
Burrowing Crayfish Species Mapped
Genetic Analysis Suggests Dwarf Crayfish Share Ancestor
Since most dramatic genomic changes are caused by genome rearrangements as well as gene duplications and gain/loss events, it becomes crucial to understand their mechanisms and reconstruct ancestral genomes of the given genomes.
In this study, researchers mapped the habitat and evolutionary lineage of burrowing crayfish by analyzing five genes in 19 species of Fallicambarus. The genus Fallicambarus consists entirely of primary burrowers-- crayfish that inhabit burrows for all of their lives. The burrows can have a negative impact when their habitat overlaps with human land-based activities such as farming. Because Fallicambarus is distinct from stream-based crayfish species, habitat shift may impact migration, speciation and conservation.
Though similar in appearance, researchers were unsure if Dwarf crayfish found in distinct locations along the Gulf Coast of United States and into Central México were members of a the same taxonomic genus. Analysis of samples collected at 59 locations support the hypothesis that the Gulf and Mexican Groups shared a common ancestor roughly 40 million years ago. It is likely that the Cambarellus genus became separate groups following changes in geographical barriers and climate, possibly related to the Eocene-Oligocene boundary.
The Computational Biology Institute is proud to partner with:
Karna supports Federal agencies in the areas of science, research,
technology, lab, communications, and management consulting.
AMPEL BioSolutions interrogates, analyzes, synthesizes and
interprets the world's biomedical knowledge to provide novel
solutions for clinical research questions.
Professor Keith Crandall, Director of the Computational Biology Institute, was interviewed for an article in the Washington Post.
Jimmy Bernot, PhD student and graduate research assistant with the Computational Biology Institute, was awarded the 2017 Edward & Phyllis Reed Fellowship.
Assistant Research Professor Marcos Perez-Losada was published in Genetics and Evolution of Infectious Diseases in April 2017.
Marcos Perez-Losada and co-authors published "Nasopharyngeal microbiome in premature infants and stability during rhinovirus infection" in the Journal of Investigative Medicine.
Professor Keith Crandall, Director of the Computational Biology Institute, was recently interviewed for an article by Beth Baker, "Big Data Opens Promising Career Paths for Biologists".