Members of the CBI, including postdoctoral researcher Dr Nikita Alexeev, PhD student Pavel Avdeyev, and CBI faculty member Dr Max Alekseyev, have published an article in BioMed Central.
Several GW researchers, including CBI Director Dr. Keith Crandall, received funding from the National Cancer Institute to look at the impact of human endogenous retroviruses in certain cancers.
Dr. Keith Crandall, Director of the Computational Biology Institute, is quoted in this article about the continuing successes of researchers at GWU.
Dr. Keith Crandall, Director of the Computational Biology Institute at The George Washington University, will be participating in the Joint GW Children's National Informatics Seminar Series, on the subject of "Computational Approaches for Biodiversity Informatics".
DC CFAR Investigator, Amanda Castel, MD, MPH, and Marcos Perez-Losada, PhD, MS Receive NIH CFAR Administrative Supplement
CBI member Dr. Marcos Perez-Losada and his colleague Dr. Amanda Castel have received a NIH CFAR Administrative Supplement, concerning HIV transmission research in Washington, D.C.
About the CBI
Bruins-In-Genomics (B.I.G.) Summer is an intensive, practical experience in genomics and bioinformatics for Undergraduate students who are interested in integrating quantitative and biological knowledge, and pursuing graduate degrees in the biological, biomedical or health sciences. For more information, click the link above.
A call has been made for applications to a fellowship for those interested in genomics and biodiversity. Click the link above for more information about the call!
The Smithsonian's National Museum of Natural History will be hosting "BioGenomics2017: The Global Biodiversity Genomics Conference" from February 21st-23rd. Sign up at the link above!
The Howard Hughes Medical Institute (HHMI) has announced a new program to recruit and retain early-career scientists who are from gender, racial, ethnic, and other groups underrepresented in the life sciences, including those from disadvantaged backgrounds. Click the link above for more information!
The NIH Big Data to Knowledge program has announced a series of online lectures. Click the link above for more details.
Reconstruction of Ancestral Genomes in Presence of Gene Gain and Loss
Burrowing Crayfish Species Mapped
Genetic Analysis Suggests Dwarf Crayfish Share Ancestor
Since most dramatic genomic changes are caused by genome rearrangements as well as gene duplications and gain/loss events, it becomes crucial to understand their mechanisms and reconstruct ancestral genomes of the given genomes.
In this study, researchers mapped the habitat and evolutionary lineage of burrowing crayfish by analyzing five genes in 19 species of Fallicambarus. The genus Fallicambarus consists entirely of primary burrowers-- crayfish that inhabit burrows for all of their lives. The burrows can have a negative impact when their habitat overlaps with human land-based activities such as farming. Because Fallicambarus is distinct from stream-based crayfish species, habitat shift may impact migration, speciation and conservation.
Though similar in appearance, researchers were unsure if Dwarf crayfish found in distinct locations along the Gulf Coast of United States and into Central México were members of a the same taxonomic genus. Analysis of samples collected at 59 locations support the hypothesis that the Gulf and Mexican Groups shared a common ancestor roughly 40 million years ago. It is likely that the Cambarellus genus became separate groups following changes in geographical barriers and climate, possibly related to the Eocene-Oligocene boundary.
CBI Transitions to the Milken Institute School of Public Health
The Computational Biology Institute is highlighted in the Milken Institute School of Public Health's "2016 Progress Report" as we make the exciting transition into the organization. Check us out on page 17!