About CBI

Now more than ever before, the power to turn huge volumes of data into information about our world has put the answers to some of life’s most challenging questions within our grasp. The George Washington University’s Computational Biology Institute (CBI) brings together leading faculty in biology, medicine and computing to harness this information, opening new doors of discovery that have the potential to benefit millions. CBI is also maximizing the university’s unique relationships in the nation’s capital to form research partnerships and spotlight cutting-­‐edge topics that enhance human and environmental health. By blending its own skills with the expertise of engineers, mathematicians, statisticians, clinicians and others, the CBI is contributing to knowledge and resources that are used by researchers on a global scale, influencing how the world uses science and technology to solve its most pressing problems. With these truly incomparable resources and expertise, the CBI performs cutting-edge research and helps raise awareness of scientific advancements that improve our health, environment and overall quality of life.




U.S. News & World Report's List of Best Public Health Graduate Programs


Washington D.C.'s only Public Health School


Shaping Public Health Policy and Practice


130 Full-time Faculty Leading our Students, and 300 Part-time Faculty.


Featured Publications


546 Therapeutic beta-lactam dosages and broad-spectrum antibiotics are associated with short-term reductions in microbial richness and beta-diversity

December 4, 2023

People with cystic fibrosis have morbid pulmonary exacerbations. Antibiotics are common, yet the beta-lactam doses administered are less than half the time.

Host taxonomy determines the composition, structure, and diversity of the earthworm cast microbiome under homogenous feeding conditions

December 4, 2023

Host evolutionary history is a key factor shaping the earthworm cast microbiome, although its effect can be shadowed by the earthworm’s diet.

Induction of mastitis by cow-to-mouse fecal and milk microbiota transplantation causes microbiome dysbiosis and genomic functional perturbation in mice

December 4, 2023

To understand the host-tropism phenomena of bovine-tropic mastitis microbiomes, we developed a cow-to-mouse mastitis model.

Differential expression of single-cell RNA-seq data using Tweedie models

December 4, 2023

To model the technological variability in cross-platform scRNA-seq data, here we propose to use Tweedie generalized linear models.


Explore More Publications




We developed omeClust, a generic tool for omics community detection, and applied it to the dissimilarity matrix of the genetic sequences of previous strains of this coronavirus to the newest ones, identifying the sites of genetic difference.


Earth Biogenome Project

The CBI works closely with the EBP, which proposes to sequence all life on earth! Click the image above to find out more about the project.

Global Invertebrate Genomics Alliance

GIGA is a collaborative network of researchers seeking to tackle major scintific challenges in the field of genomics. To find out more, click on the link above.


FDA-ARGOS database updates may help researchers rapidly validate diagnostic tests and use qualified genetic sequences to support future product development.