Featured Publications
Get to know some of the latest publications by our faculties.
Metabolite, protein, and tissue dysfunction associated with COVID‑19 disease severity
July 16, 2022
Proteins are direct products of the genome and metabolites are functional products of interactions between the host and other factors.
High-sensitivity pattern discovery in large, paired multiomic datasets
June 27, 2022
We present a novel framework which integrates hierarchical hypothesis testing with FDR correction to reveal linear and non-linear relationships among data.
Association of Early Aspirin Use With In-Hospital Mortality in Patients With Moderate COVID-19
March 24, 2022
Prior studies suggest aspirin may be associated with reduced mortality in high-risk patients with COVID-19, but patients with moderate COVID-19 are not studied.
546 Therapeutic beta-lactam dosages and broad-spectrum antibiotics are associated with short-term reductions in microbial richness and beta-diversity
October 1, 2022
People with cystic fibrosis have morbid pulmonary exacerbations. Antibiotics are common, yet the beta-lactam doses administered are less than half the time.
Host taxonomy determines the composition, structure, and diversity of the earthworm cast microbiome under homogenous feeding conditions
August 4, 2022
Host evolutionary history is a key factor shaping the earthworm cast microbiome, although its effect can be shadowed by the earthworm’s diet.
Induction of mastitis by cow-to-mouse fecal and milk microbiota transplantation causes microbiome dysbiosis and genomic functional perturbation in mice
July 6, 2022
To understand the host-tropism phenomena of bovine-tropic mastitis microbiomes, we developed a cow-to-mouse mastitis model.
Differential expression of single-cell RNA-seq data using Tweedie models
June 2, 2022
To model the technological variability in cross-platform scRNA-seq data, here we propose to use Tweedie generalized linear models.