Jobs in Computational Biology

***POSTED 2/12/18***

Biological Science Laboratory Technician (Analytical Biology)

Please review the posting at this link: https://www.usajobs.gov/GetJob/ViewDetails/490597500

***POSTED 2/8/2018***

Postdoctoral Scientist

Job Posting at https://www.gwu.jobs/postings/49199

Application Review Begins February 20th, 2018

The Computational Biology Institute in George Washington University’s Milken Institute School of Public Health is seeking a highly motivated Postdoctoral Scientist (PDS). The work performed by the PDS will contribute to our diverse research program devoted to the investigation of: i) the role of microbial infection and host immunity in the etiology of respiratory and gastrointestinal disorders and ii) the impact of microbiomes in natural and artificial ecosystems.

The PDS will focus on Omic-based research (metagenomics, metatranscriptomics and transcriptomics) on two main topics: i) the impact of microbial diversity and function on human heath (host-microbe interactions), and ii) the ecological role of microbes in soil-plant ecosystems (microbe-environment interactions).

These studies are part of ongoing collaborations between national (Children’s National Hospital, Washington DC) and international institutions (University of Vigo, Spain and Universidad Andres Bello, Chile) and the Computational Biology institute, George Washington University.

The selected candidate will be based on the Computational Biology Institute in Washington DC. For further information about the Computational Biology Institute at George Washington University, please seehttp://cbi.gwu.edu. All applications for consideration must be submitted online but for questions relating to this opportunity, please contact Dr. Pérez-Losada, Computational Biology Institute, Milken Institute School of Public Health, The George Washington University, at mlosada@gwu.edu.

Responsibilities Include:

- Design and carry out analysis of high-throughput sequencing data (16S rRNA, DNAseq and RNAseq) 
- Engage in research projects on the basis of the analysis of sequencing data
- Collaborate with other lab members in the development of strategies for high-throughput sequencing data analyses
- Prepare research papers and presentations to disseminate research results through academic journals and conferences
- Work with other lab members on projects as assigned
- Performs other related duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position.

Preferred Qualifications:

- Applicants must possess a PHD in a relevant discipline (Computational Biology, Bioinformatics, Microbiology and Microbial Ecology), with experience in Genomic and Systems Biology analyses and an understanding of the key issues and relevant tools in the field.

- A good understanding of multivariate statistics is essential.

- A strong quantitative background and good programming skills (R, Python/Perl), Big data managing and integration are all required

- Experience with DNA and RNA extraction and sequencing is useful but not essential.

***POSTED 2/8/2018***

Research Associate, Software Development (Software Engineer)

https://www.gwu.jobs/postings/49354

Job Description Summary:

The Computational Biology Institute (CBI) at George Washington University is seeking a Research Associate in Software Development to contribute to ongoing research projects and developing diverse tools for analyzing omic data. The successful candidate will have a background in computer science and informatics, and will have programming experience in Python, C/C++, JAVA, and/or R. This position will report to the Director of CBI (Keith Crandall, kcrandall@gwu.edu). The software development is part of an NIH funded collaborative effort in informatics at the Clinical and Translational Science Institute Children’s National (CTSI-CN, https://www.ctsicn.org/).

Responsibilities include:
- Manage the development of new software modules
- Lead communication efforts with members of the Institute to understanding existing needs and forecast the future requirements of software development
- Develop educational modules, tutorials, and workshops for training purposes
- Develop and manage databases and interface for DNA sequence analysis, and develop and implement tools for omics analysis within a comprehensive pipeline framework

Minimum Qualifications:

Qualified candidates will hold a Master’s degree and 1 year of experience in a related discipline. Degree must be conferred by the start date of the position.

Preferred Qualifications:

A Bachelor’s in computer science or a related field is required, or an equivalent combination of education, training and experience. Master’s in computer science, data science or related field is preferred, with two years experience. The successful candidate will have experience in multiple programming languages with some applications to bioinformatic analyses. Experience with clinical health data is also a plus. Application review will begin March 1, 2018.

***POSTED 2/8/2018***

Research Scientist, NGS Core

Job Posting at https://www.gwu.jobs/postings/49245

Application Review Begins February 20th, 2018


The Computational Biology Institute in the Milken Institute School of Public Health at The George Washington University is seeking a highly-motivated candidate for a position as a Research Scientist with the Next-Gen Sequencing (NGS) Core. A successful applicant will be ready and willing to assist with the startup for a brand-new facility and to guide the facility toward strong operations. The Core already possesses some of the most cutting-edge equipment necessary, with the goal of processing thousands of samples per year. The applicant should be prepared to lead the facility further still with regards to building up the resources of the Core and to hire new staff members.

Responsibilities Include:

- Lead the collaboratively efforts with faculty, staff, students, and collaborators
- Lead the design of comprehensive project objectives
- Manage the evaluation of data analytics and formulate informatics solutions; 
- Manage collaborative relationship relationships of key stakeholders to build a robust research infrastructure;
- Develop and implement bioinformatics analyses, applications, and workflows; 
- Integrate statistical analyses to project design and data interpretations;
- Manage NGS data analysis and delivery, pipeline development and automation;
- Provide customer support for NGS data analysis results; 
- Manage the sale and marketing of the NGS Core;
- Performs other related duties as assigned. The omission of specific duties does not preclude the supervisor from assigning duties that are logically related to the position.

Minimum Qualifications:

Qualified candidates will hold a master’s degree/PhD and at least 5 years of experience in a related discipline, to include at least 2 years of research and/or college level teaching in a field basic to the work to be performed. Degree must be conferred by the start date of the position.

Preferred Qualifications:

- Master’s degree in life sciences or related field required, Ph.D. preferred
- Two or more years of related genomics experience required
- Essential knowledge of key biological processes and NGS technology desired
- Concrete bioinformatics skills in analysis of data from various omic platforms
- Experience in NGS data generation and analysis
- Experience with the Illumina sequencing platform, especially MySeq and NextSeq
- Two years of documented hands-on (wet lab) experience with NGS assay development, validation, troubleshooting, and reviewing of run QC data.
- In-depth knowledge of different NGS platforms and technologies (experience with long reads sequencing is a plus).
- Familiar with different NGS software platforms, bioinformatics pipelines and NGS data processing and interpretation solutions.
- Technical expertise with other molecular technologies, including but not limited to: PCR, quantitative real-time PCR, digital PCR, NanoString, etc. is also highly desired.
- Strong organizational and interpersonal skills, must display excellent leadership and people skills, and demonstrate ability to work collaboratively with others in a highly matrixed environment.
- Self-motivated, demonstrated ability to work independently and learn quickly.
- Goal oriented and focused on completing work on time.
- Thrive in a highly interactive, fast-paced and dynamic team environment.
- Able to quickly adapt to changing priorities and work well in fast pace environment and under pressure.
- Fluent in English both oral and written and possess good communication and presentation skills.
- Full understanding of laboratory requirements, SOPs, ICH guidelines, USP requirements and FDA guidance
- Full knowledge of technical operating systems
- Ability to independently optimize analytical methods
- Ability to independently perform root cause analysis for method investigations
- Proven ability in technical writing skills
- Proven problem solving and troubleshooting abilities
- Effective written and oral communication skills as well as presentation skills
- Time management and project management skills
- Ability to mentor others on technical operating systems
- Ability to independently review and understand project proposals/plans