Crandall Published in Scientific Reports

August 22, 2017

Professor Keith Crandall co-authored "Overexpressed somatic alleles are enriched in functional elements in Breast Cancer," which was published in Scientific Reports on August 15th, 2017. Notably, they find frequent allele-specific overexpression of variants in tumor-suppressor genes. They also report a list of over-expressed variants from non-CGC genes. Overall, their analysis presents an integrated set of features of somatic allele expression and points to the vast information content of the asymmetric alleles in the cancer transcriptome.